Since the half-life is so long I think you should start by skipping the pill every other day, then skip and only take it every two days, then 3, then so on.I don't think cutting the dose and taking it every day is necessary. Best Answer: Yes. Due to the half life of prozac, taking one 20mg capsule every other day will be like having 10mg per day in your system. How is taking 40mg and 20mg of prozac on alternate days different than taking 30 mg/day?. and most every medication has something that is unique to itself. And if mixed with another compound you just don't know. There are websites that can help with medications, explains the medicatio in question and will explain one medication taken with another. I can't recall a site. But if you just. I take Prozac 20mg. I started two months ago. A month ago I switched to taking it every other day (by doc) because she thought it was making me manic. I would like to try 10mg every other day so 5mg daily to start. I have read that the half life is very long with Prozac which is why some are able to do every other day dosing. I have read that the half life is very long with Prozac which is why some are able to do every other day dosing. hello,i have read any other peoples suggestions on this topic,im 19 weeks pregant and taking a low dose of prozac,i shuld take them every day but have managed to cut them down to just 3 tablets a week due to being pregant as i feel i am unable to stop taking them all together,i take them due to panic attacks.will my baby be ok? There are numerous other categories of antidepressants such as the SNRI's, DNRI's or the tricyclics. You are on an extremely low dose of Prozac. Once the fluoxetine (Prozac) blood level is stable, someone that is stable on 20mg a day could probably be OK with 40mg every other day. There is also a formulation to take fluoxetine once a week. Because individual metabolism varies, the dosage might not be exact. Taking it that way may also cause more side effects because the blood level will rise a bit more after each dosage. No it's not the same, but.taking it every other day might be the way to go for you. These meds all have half-lives or something like that. Wellbutrin for example is 18 hours or something like that. Hi everyone, Ive experienced euphoric feeling first week taking prozac and then I usually become depressed over time, but ive noticed taking it every other.